Perform a Sample Analysis

 

In 21CFR11 environments, users are required to login to the Confirm application to start an analysis. Once the analysis window is opened, manual control is disabled until the analysis has completed. During analysis, pausing and resuming is allowed, however, steps cannot be skipped.

Use to perform up to three analyses with different analysis conditions and/or report options. Sample files can be loaded into ports 1, 2, and 3 allowing one analysis using different analysis conditions to run on each port.

When Start is selected, the selected sample file’s analysis conditions will be compared with the port’s hardware configuration to verify that the specified analysis is supported by the hardware:

  • If Krypton is selected as the adsorptive, there must be a 10 mmHg transducer present on the port.
  • The minimum target pressure must be no less than the Minimum Record Pressure for the minimum range transducer present on the port.
  • The selected sample files will be checked for matching adsorptive gases, matching Psat or P0 gases if measured, and matching backfill gases. All selected gases, except those in a precharged vapor source, must be connected to gas inlets and identified on the Unit [n] > Unit Configuration > Gas Selections window. See Specify Gas Ports and Unit Configuration.
  • If any selected sample file specifies an Adsorptive Dose Method from port 3 and a sample file is selected for port 3, an error message displays indicating the problem and the Start window will remain active.
  1. Click Close Valves to manually close all analyzer valves.
  2. For a selected port, either click Browse and select a sample file, or click New to create a new sample file.
  1. Verify the information populated into the sample identification. This information is pulled from the selected or newly created sample file. The Density value is applicable only if using the Calculate method for the free space determination.
  2. Edit the P0 and Bath temperature fields, if necessary.
  3. If using a cryostat, select Use CryoStat and complete the Target tolerance and Hold time fields.
  4. Click Report after analysis to generate reports automatically when the analysis is complete.
  5. On the Report Settings window, select the report destination. Click OK to return to the previous window.
  6. Click Start to start the analysis. A window displays data as they are collected. A short delay is encountered before the port status at the bottom of the window changes from the Idle state.
  1. When the analysis is complete, remove the sample tube and store (or dispose of) the sample material as applicable.
  Use caution when removing the sample tube if using a hanging filler rod. The sample tube O-ring or Dewar cover may snag the filler rod retaining ring. Loosen the snag gently as excessive force may break the tip of the filler rod.
Sample Analysis Graph
Selections Description
Bath temperature [text box] Enter the temperature for the analysis bath.
Close Valves [button] Closes all valves on the unit.
Density / Mass / Sample + Tub[text box]e / Empty Tube Enter values for the sample’s mass and density. These values may be edited after analysis.
New [button] Creates a new sample file.
P0 [text box] Enabled if Entered is selected for the P0 measurement for at least one file.
Report after analysis [button] Generates reports to the selected destination when the analysis is complete.
  For fields and buttons not listed in this table, see Common Fields and Buttons.

 

  1. Suspend/Resume/Skip
    buttons
  2. Port report buttons
  3. Live graph settings
Sample Analysis Graph
Selections Description
Port [button]

Generates a report on data being collected on the respective port. The reports are displayed on the computer monitor only.

Live Graph Settings
[button]
Select Thermal transpiration, x-axis Quantity (relative or absolute pressure), and the x-axis Scale (linear or logarithmic).
Report after analysis [button] Generates reports to the selected destination when the analysis is complete.
Status window Displays the last point pressure and relative pressure for each port with varying numbers of digits after the decimal if 10 mmHg and 0.1 mmHg transducers are present on that port, as follows: P < 0.1: 6 digits, 0.1 <= P < 10: 4 digits, P >= 10: 2 digits. Relative pressure will show 3 more digits than absolute pressure.
  For fields and buttons not listed in this table, see Common Fields and Buttons.